Germ plasm, the Balbiani body and nuage are evolutionary conserved structures essential for germ cell specification and maintenance. We describe Tdrd6a as a component of these structures with two dist

NIAID Data Ecosystem20

Gonad mRNA sequencing of pie-1 mutants in C. elegans

生殖细胞发育

基因表达谱分析

Gonad mRNA sequencing of pie-1 mutants in C. elegans

NIAID Data Ecosystem20

The zinc-finger protein OEF-1 stabilizes patterns of activating and silencing modifications in the C. elegans germ line

表观遗传调控

生殖细胞发育

Sex-determining chromosomes exhibit complex global regulation in germ cells, in part due to the absence of dosage compensatory mechanisms found in the soma. In the XX hermaphrodite germ line of C. ele

NIAID Data Ecosystem30

Single-Cell Transcriptome Analysis of Rb1 Conditional Knockout Prospermatogonia

单细胞转录组学

生殖细胞发育

Prospermatogonia, precursors to the mature male germline, undergo a period of sustained quiescence during late fetal and early postnatal development. The purpose of this mitotic arrest is not fully un

NIAID Data Ecosystem20

Double strand break formation as measured by γ-His2Av staining.

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