Human aldose reductase mutant F121P complexed with zopolrestat.
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Human aldose reductase mutant F121P complexed with zopolrestat. Descriptor: 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Steuber, H, Heine, A, Klebe, G. Deposit date: 2007-03-31 Release date: 2008-04-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features. J.Mol.Biol., 379, 2008
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2007-03-31
