Graph image of the metabolic network.

Each reaction in the network was a priori assigned to one of 10 textbook pathways as described in Methods. The pathway assignments are indicated by the color of the reaction vertex in the network. (TRANS: transport; DETOX: detoxification; GLYCO: glucose metabolism; PYRU: pyruvate metabolism; TCA: tca cycle; UREA: urea cycle; ROP: oxidative phosphorylation; LIPID: lipid metabolism; AA: amino acid metabolism; KET: ketone body metabolism).