KRasG12C ligand complex
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KRasG12C ligand complex Descriptor: 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Phillips, C. Deposit date: 2019-10-17 Release date: 2020-02-19 Last modified: 2025-10-01 Method: X-RAY DIFFRACTION (1.31 Å) Cite: Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C. J.Med.Chem., 63, 2020
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2019-10-17
