Impact of TNF-alpha 308G_A and 857C_T variants on susceptibility to chronic HBV infection in Mauritanian patients

his study investigates genetic polymorphisms within the tumor necrosis factor (TNF) gene cluster and their association with chronic hepatitis B virus (HBV) infection. Two single nucleotide polymorphisms (SNPs), TNF-alpha -308G>A (rs1800629) and -857C>T (rs1799724), were analyzed to evaluate their possible role in HBV infection outcomes among Mauritanian patients.