Consistency of three clustering methods with EC assignments

aTotal proteome size = 112,920. bEnzyme groups are defined as groups with at least two proteins for which EC annotation is available. cA total of 4,739 proteins have EC annotations according to ENZYME database. dAll EC-annotated proteins in the group have the same or consistent EC numbers. Percentages indicate fraction of enzyme groups which are consistent in EC annotation, or fraction of EC-annotated proteins properly put into consistent groups.