The rapid adoption of next-generation sequencing in clinical oncology has enabled detection of molecular biomarkers which are shared between multiple tumour types. Intra-tumour heterogeneity is a mech

DataCite Commons2024-03-21 更新30

Table_4_RNA Sequencing Revealed Signals of Evolution From Gallbladder Stone to Gallbladder Carcinoma.XLSX

癌症基因组数据

生物标志物发现

Gallbladder stone is a major risk factor for gallbladder carcinoma (GBC), while there is still a controversy whether period of follow-up since newly diagnoses of asymptomatic gallstones increases the

NIAID Data Ecosystem10

p53 gene mutation: software and database.

p53基因突变数据库

癌症基因组数据

A large number of different mutations in the tumor suppressor gene p53 gene have been identified in all types of cancer. As of September 1995, this database contains over 4200 mutations. This substant

PubMed Central1996-01-01 更新00

Genotype status of mutations and SNPs identified in GRM1 gene in matched prostate tumor-normal tissues.

癌症基因组数据

突变体测序

aDSSC: Downstream to stop codon.

Figshare2015-12-02 更新20

Table 2_KEAP1 mutations activate the NRF2 pathway to drive cell growth and migration, and attenuate drug response in thyroid cancer.xlsx

癌症基因组数据

靶向治疗耐药性

The KEAP1/NRF2 pathway, a major regulator of the cellular oxidative stress response, is frequently activated in human cancers. Often mediated by loss-of-function mutations in KEAP1, this activation ca

NIAID Data Ecosystem00

WES of 13 FFPE breast tumor samples and 13 corresponding frozen samples

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