NK cells stochastically express a range of inhibitory and activating receptors that balance their effector functions. Of these receptors, the KIRs are the most polymorphic, with KIR3DL3 present at two
PurposeA mouse model of irradiation (IR)-induced heart injury was established to investigate the early changes in cardiac function after radiation and the role of cardiac macrophages in this process.
BackgroundVitiligo is a common autoimmune depigmented dermatology due to destruction of melanocytes. Much evidence suggests that vitiligo is associated with systemic immune activation. Previous studie
The endocrine system severely impacts individual aging. However, its cellular signatures and underlying mechanisms have not been comprehensively elucidated. Here, we present a comprehensive single-cel
