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Transcriptome changes in human endothelial cells with reduced cMYC signaling.. Transcriptome changes in human endothelial cells with reduced cMYC signaling.

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NIAID Data Ecosystem2026-03-12 收录
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Transcriptome profiling of human umbilical vein endothelial cells (HUVECs) transduced with lentiviruses encoding FLAG-CAS9 nuclease and control- (gCTL) or cMYC-targeting (gMYC) gRNAS to identify cMYC regulated genes. Overall design: HUVECs were engineered by CRISPR/CAS9 to ablate cMYC expression. A pool of stable cells for control and MYC-depleted HUVECs was selected after puromycin treatment.

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2020-11-19
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