Whether a gene involved in distinct tissue or cell functions exerts a core of common molecular activities is a relevant topic in evolutionary, developmental, and pathological perspectives. Here, we ad
3D Caco-2 spheroids were incubated with cell culture medium (control), 32 ug/mL MoS2 nanosheets (MoS2-2D) and 32 ug/mL MoS2 powder (MoS2-bulk) for 24 h, and transcriptomic analysis was done to reveal
Cancer cells that express oncogenic alleles of RAS typically require sustained expression of the mutant allele for survival, but the molecular basis of this oncogene dependency remains incompletely un
Background: in clear cell renal cell carcinoma (ccRCC), 80% of cases have biallelic inactivation of VHL gene, leading to constitutive activation of both HIF1a and HIF2a. As HIF2a is the driver of the
