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Contribution of Cellular Metabolism to Neural Crest Cell Development

NIAID Data Ecosystem2026-03-14 收录

神经嵴细胞发育

细胞代谢调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA883392 数据链接链接失效反馈

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We hypothesized that cellular metabolism is a modifier of neural crest cell biology/physiology. To test this hypothesis, we performed RNA-seq with murine O9-1 cells cultured in various concentrations of glucose and pyruvate.

应用场景：

创建时间：

2022-09-22

细胞代谢调控

葡萄糖应激反应

Cells were serum-starved with 0.1mM glucose (1mM pyruvate) for 24 h. The glucose was withdrawn (basal) or increased to 2.5 mM for 3 h. Raw data set 1-3 is basal, 4-6 glucose stimulation

NIAID Data Ecosystem60

The single-cell transcriptomic landscape of cardiac neural crest cell derivatives during embryonic and early postnatal development

神经嵴细胞发育

单细胞转录组学

Cardiac neural crest cells (CNCCs), have been demonstrated to play essential roles in cardiovascular development. A thorough understanding of the cell types, transcriptomic states and regularity netwo

NIAID Data Ecosystem20

GSH-deficiency promotes basal hyperinsulinemia in the insulin secreting cell line INS-1

胰岛素分泌机制

细胞代谢调控

This study sought to determine the impact of glutathione (GSH) synthesis on beta-cell function. To induce GSH deficiency, GCLC was inhibited in INS-1 cells using buthionine sulfoximine (BSO). The 24-h

NIAID Data Ecosystem10

Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion

HIV-1病毒融合机制

细胞代谢调控

There has been resurgence in determining the role of host metabolism in viral infection yet deciphering how the metabolic state of single cells affects viral entry and fusion remains unknown. Here, we

NIAID Data Ecosystem30

DataSheet1_Epigenetic Modifier Supplementation Improves Mitochondrial Respiration and Growth Rates and Alters DNA Methylation of Bovine Embryonic Fibroblast Cells Cultured in Divergent Energy Supply.docx

表观遗传修饰

细胞代谢调控

Epigenetic modifiers (EM; methionine, choline, folate, and vitamin B12) are important for early embryonic development due to their roles as methyl donors or cofactors in methylation reactions. Additio

NIAID Data Ecosystem20

Contribution of Cellular Metabolism to Neural Crest Cell Development

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