Background: Volumetric absorptive microsamples (VAMS) can support pharmacokinetic /pharmacodynamic studies. We present the bioanalytical method development for the simultaneousquantification of ampici
The protocol of a clinical study aimed at the characterization of the pharmacokinetics of piperacillin and tazobactam and its association with the concentrations of inflammatory markers and adrenal st
CLva: vancomycin clearance. CLcr: creatinine clearance calculated from serum creatinine with Cockcroft and Gault [11]. Vd: volume of distribution. Mean (±SD) for Age, CLcr, CLva, Vd, Creatinine for pa
The pharmacokinetic properties of meropenem were investigated in nine critically ill patients treated by continuous venovenous hemofiltration (CVVH). All patients received one dose of 1 g of meropenem
Background: Due to the heterogeneity of critically ill patients, the pharmacokinetics of tigecycline are unclear, and the optimal dosing strategy is controversial. Methods: A single-center prospective
