CancerDR: CancerDR: Cancer Drug Resistance Database

CancerDR was developed to address one of the major challenges in cancer treatment — acquired drug resistance. The database compiles pharmacological response data of anticancer drugs across diverse cancer cell lines along with mutation profiles, structural information, and sequence analysis of drug targets. The resource supports personalized medicine approaches by helping researchers identify mutations responsible for drug resistance and discover drugs effective against specific cancer types. Web Server: https://webs.iiitd.edu.in/raghava/cancerdr/ Citation Kumar, R., Chaudhary, K., Gupta, S., et al. (2013). CancerDR: Cancer Drug Resistance Database. Scientific Reports, 3, 1445. https://doi.org/10.1038/srep01445 About the Database CancerDR integrates pharmacological profiling data of anticancer drugs with mutation and structural information of drug targets. The database contains: 148 anticancer drugs 952 cancer cell lines 116 drug targets 1356 mutations Data were collected from resources such as: COSMIC CCLE PubChem UniProt