Cryo-EM structure of spyCas9-sgRNA-DNA dimer
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Cryo-EM structure of spyCas9-sgRNA-DNA dimer Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (49-MER), RNA (115-MER) Authors: Liu, J, Deng, P. Deposit date: 2021-08-16 Release date: 2022-08-17 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (5.26 Å) Cite: Nonspecific interactions between SpCas9 and dsDNA sites located downstream of the PAM mediate facilitated diffusion to accelerate target search. Chem Sci, 12, 2021
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2021-08-16
