This study aims to investigate the role of p53 in cardiac hypertrophy. We constructed a cardiac hypertrophy model using both wild-type (WT) and p53 knockout (KO) mice subjected to transverse aortic co

NIAID Data Ecosystem30

Chromatin dynamics of p53 binding sites in IMR90

染色质修饰动态

p53基因调控

We report the chromatin modification dynamics at p53 binding sites upon treatment with DMSO or nutlin3-a (5uM) in IMR90 human lung fibroblasts using ChIP-seq and RNA-seq analyses. We assessed the geno

NIAID Data Ecosystem70

Unirradiated HCT116-Clone2 cells. Homo sapiens

辐射抗性机制

cDNA微阵列表达谱

cDNA microarray study of unirradiated X-radiation (XR) resistant HCT116-Clone2 cells versus unirradiated HCT116-Clone10 cells. HCT116-Clone10 cells have similar XR response with parental HCT116 cells.

NIAID Data Ecosystem40

Expression profiling of p53-regulated genes by cDNA microarray analysis

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