Transcriptional programs dictating Schwann cell transformation in MPNST
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2022-11-08
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MicroRNA expression profiles in sporadic malignant peripheral nerve sheath tumors. MicroRNA expression profiles in sporadic malignant peripheral nerve sheath tumors
Malignant peripheral nerve sheath tumors (MPNST) are aggressive cancers that occur spontaneously (sporadic MPNST) or from pre-existing, benign plexiform neurofibromas in neurofibromatosis type 1 (NF1)
NIAID Data Ecosystem70
Microarray Analysis in Vestibular Schwannomas. Homo sapiens
Vestibular Schwannomas are benign neoplasms that arise from the vestibular nerve. The hallmark of these tumors is the biallelic inactivation of NF2. Transcriptomic alterations, such as the Nrg1/ErbB2
NIAID Data Ecosystem50
Gene expression profile at single cell level of vestibular schwannoma. Gene expression profile at single cell level of vestibular schwannoma
Vestibular schwannoma (VS) is the most common benign tumor in the cerebellopontine angle and internal auditory canal. Illustrating the heterogeneous cellular components of VS could provide insights in
NIAID Data Ecosystem30
Expression data of three sets of cells: (1) Schwann cells and macrophages from 1m-old WT DRG, (2) Schwann cells (Nf1-/-) and macrophages (Nf1+/+) from 1m-old neurofibroma, (3) Schwann cells (Nf1-/-) and macrophages (Nf1+/+) from 7m-old neurofibroma
Schwann cells and macrophages were dissociated from normal DRGs and 1- and 7-month-old neurofibroma. Schwann cells from neurofibroma have Nf1-/- phenotypes. All macrophages have Nf1+/+ phenotypes. We
NIAID Data Ecosystem50
2d44e68f-f9a3-4956-ad4a-983437293dd7 - samples
WES from 51 cases initially diagnosed as Malignant Nerve Sheath Tumours (MPNST) and RNA sequencing data from 10 MPNST cases. Find more information in article: Lyskjær et al, 2020, J Pathol, "H3K27me3
NIAID Data Ecosystem40
