首页/数据集/STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION

STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION

NIAID Data Ecosystem2026-05-01 收录

蛋白-药物复合物结构解析

艾滋病药物设计

数据链接：

https://www.rcsb.org/structure/1HNI 数据链接链接失效反馈

官方服务：

资源简介：

STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION

应用场景：

创建时间：

2024-02-07

艾滋病药物设计

整合酶抑制剂

More than 15,000 Australians and 40 million people worldwide are currently infected with HIV, which leads to acquired immunodeficiency syndrome (AIDS). HIV treatments are available that slow the progr

Research Data Australia60

DETERMINATION OF THE NMR SOLUTION STRUCTURE OF THE CYCLOPHILIN A-CYCLOSPORIN A COMPLEX

蛋白-药物复合物结构解析

核磁共振结构解析

DETERMINATION OF THE NMR SOLUTION STRUCTURE OF THE CYCLOPHILIN A-CYCLOSPORIN A COMPLEX Descriptor: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A Authors: Spitzfaden, C, Braun, W, Wider, G, Widm

Protein Data Bank Japan2025-03-26 更新40

Small molecule inhibitors of the LEDGF site of HIV type 1 integrase identified by fragment screening and structure based drug design

艾滋病药物设计

整合酶抑制剂

Small molecule inhibitors of the LEDGF site of HIV type 1 integrase identified by fragment screening and structure based drug design Descriptor: 5-[[[2-[[(1S)-1-(4-METHOXYPHENYL)BUTYL]CARBAMOYL]PHENYL

Protein Data Bank Japan2023-12-20 更新20

Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors

艾滋病药物设计

先导化合物

Integrase mutations can reduce the effectiveness of the first-generation FDA-approved integrase strand transfer inhibitors (INSTIs), raltegravir (RAL) and elvitegravir (EVG). The second-generation age

NIAID Data Ecosystem60

HIV Integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid

HIV整合酶抑制剂

艾滋病药物设计

HIV Integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid

NIAID Data Ecosystem20