Rapid On-site SNP Discrimination Across Diverse Mutational Contexts
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A rapid diagnostic tool for field detection of single-nucleotide polymorphisms (SNPs) in under 20 minutes. Based on probe ligation at the SNP site, it generates reporter transcripts upon successful ligation. Results are visualized on LFA strips, requiring no specialized equipment, ideal for point-of-care use. The straightforward probe design minimizes testing, and the method reliably detects SNPs even with nearby mutations, validated on clinical SARS-CoV-2 samples
创建时间：
2024-09-25
