Acute kidney injury induced by cisplatin is a serious problem in clinical practice. Ammonium tetrathiomolybdate is believed to have therapeutic effects, but the exact mechanism remains unclear. In thi
The transcriptomic profile of a cell population can now be studied at the cellular level using single-cell mRNA sequencing (scRNA-seq). This novel technique provides the unprecedented opportunity to e
A single cell transcriptomic profile of bone endothelial cells of the murine femur and tibia. GFP+ tdTomato+ double positive cells were FACS-isolated from Cdh5-mTnG femur and tibia. Cells were loaded
The goal of this project was to analyze gene expression changes upon polyploidization. To this end, human U-2 OS cells were exposed to the NEDD8-activating enzyme (NAE) inhibitor Pevonedistat (MLN4924
