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Microtubule disruption targets HIF-1α mRNA to cytoplasmic P-bodies for translational repression

NIAID Data Ecosystem2026-03-10 收录

RNA定位调控

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数据链接：

https://www.omicsdi.org/dataset/bioimages/S-JCBD-201004145 数据链接链接失效反馈

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资源简介：

Live cell imaging of an untreated Hela:GFP-Ago2 cell transfected with HIF-1a MB (red).

应用场景：

创建时间：

2018-11-29

蛋白质-RNA相互作用

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Cryo-EM structure of the Hfq-Crc-amiE translation repression assembly. Descriptor: Catabolite repression control protein, RNA-binding protein Hfq, amiE Authors: Dendooven, T, Luisi, B.F. Deposit date:

Protein Data Bank Japan2024-11-13 更新80

Cellular response to small molecules that selectively stall protein synthesis by the ribosome

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核糖体暂停

We use ribosome profiling to compare the selectivity of two small molecules, PF-06446846 and PF-06378503 that inhibits translation of their target by selectively inducing ribosome-stalling in a nascen

NIAID Data Ecosystem60

Regulation of mRNA localization during the oocyte-to-embryo transition by regulated mRNA-endoplasmic reticulum association and remodeling of the endoplasmic reticulum

RNA定位调控

卵母细胞-胚胎转变

As an important post-transcriptional regulatory mechanism, asymmetric localization of mRNAs is essential for cell polarity and cell fate determination during early development. In an effort to underst

NIAID Data Ecosystem40

Homo-40S of Saccharomyces cerevisiae and its suppressors

核糖体工程

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We homogenize the cellular 40S ribosomes through deleting the whole set of alternative duplicated genes encoding yeast 40S RP paralogs. This strain(Homo-40S) shows atrong sensitivity to the translatio

NIAID Data Ecosystem80

Crystal Structure of Programmed for Cell Death 4 Middle MA3 domain

蛋白质晶体

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Crystal Structure of Programmed for Cell Death 4 Middle MA3 domain Descriptor: CHLORIDE ION, Programmed cell death protein 4, SODIUM ION Authors: Garces, R, Suzuki, C, Wagner, G. Deposit date: 2007-10

Protein Data Bank Japan2024-11-13 更新40

Microtubule disruption targets HIF-1α mRNA to cytoplasmic P-bodies for translational repression

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