Stem cell-based cardiogenesis has become a powerful tool to enhance our understanding of cardiac development and test novel therapeutics for cardiovascular diseases. However, transcriptional and epige
We have manipulated the NOTCH signaling pathway in mouse embryonic endocardial cells by the co-culture with OP9 stromal cells expressing Jag1 and Dll4, the culture over recombinant JAG1 and DLL4, and
Human heart sample data. The raw data can be found at https://www.spatialresearch.org/resources-published-datasets/doi-10-1126science-aaf2403/.(Asp, M. et al. A Spatiotemporal Organ-Wide Gene E