<b>Exposure to neodymium blunts the hypoxic ventilatory response in fathead minnows </b>

In hypoxia, the initial response in vertebrates is hyperventilation, known as the Hypoxic Ventilatory Response (HVR), which is a physiological reflex that allows fish to maintain adequate oxygen uptake to meet metabolic demands. The severity of hypoxia in aquatic ecosystems is growing due to anthropogenic impacts. This is a concern with the recent evidence that metals can affect the ability of fishes to mount the HVR. As Rare Earth Elements (REEs), such as neodymium (Nd), increase in demand with the shift to a low-carbon, green economy, there is a critical need to understand their environmental consequences. Here, we investigate whether exposure to Nd will blunt the HVR in fathead minnows (<i>Pimephales promelas</i>). Fathead minnows were exposed to 93 ± 7.9 µg/L Nd for 48-h and subjected to 40% dissolved oxygen for 1-h. The number of opercular movements were counted as a proxy of the HVR, and total Nd accumulation at the gill was characterized. Nd caused a 31% decrease in opercular breaths, and Nd accumulation in the gills was below the detection limit (LOD: 0.07 µg/L). This data demonstrates that exposure to Nd shows an effect on a fathead minnows’ ability to regulate oxygen, seen through the blunt in the HVR, potentially influencing their survivability.

在低氧环境中，脊椎动物的初始应答为过度通气，即低氧通气反应（Hypoxic Ventilatory Response, HVR）——这是一种生理反射，可帮助鱼类维持充足的氧气摄取以满足代谢需求。受人类活动影响，水生生态系统的低氧状况正日趋严重。近期研究表明，金属元素会干扰鱼类产生低氧通气反应的能力，这一发现引发了广泛关注。随着低碳绿色经济转型，钕（Nd）等稀土元素（Rare Earth Elements, REEs）的市场需求持续攀升，因此亟需厘清其潜在的环境生态效应。本研究以黑头呆鱼（<i>Pimephales promelas</i>）为实验对象，探究钕暴露是否会削弱其低氧通气反应。实验中将黑头呆鱼暴露于93 ± 7.9 μg/L的钕溶液中48小时，随后将其置于溶解氧占比为40%的水体中持续1小时。以鳃盖运动次数作为低氧通气反应的替代检测指标，并对其鳃组织中的钕总积累量进行了表征。结果显示，钕暴露使黑头呆鱼的鳃盖运动次数降低了31%，且鳃组织中的钕积累量低于检测限（LOD：0.07 μg/L）。本实验数据证实，钕暴露会通过削弱低氧通气反应，干扰黑头呆鱼的氧气调节能力，进而可能对其生存能力造成负面影响。

搜集汇总

背景与挑战

背景概述

该数据集研究了钕（一种稀土元素）暴露对黑头呆鱼缺氧通气反应的影响。实验显示，暴露于93 µg/L钕48小时后，鱼的鳃盖呼吸次数减少31%，表明钕可能削弱鱼类调节氧气的能力，从而影响其生存。数据集包括水化学、鳃重量、溶解氧、通风率和离子测量等原始数据，用于评估金属污染在缺氧环境下的生理效应。