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Lsd1 coordinates trophoblast development by retaining stem cells in their niche and directing cell fate

ChEBI2014-01-17 更新2026-07-21 收录

滋养层发育

细胞命运决定

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-38277 数据链接链接失效反馈

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Lsd1 coordinates trophoblast development by retaining stem cells in their niche and directing cell fate

应用场景：

创建时间：

2014-01-17

生殖细胞发育

细胞命运决定

To better understand the underlying dynamics driving formation of the spermatogonial stem cell (SSC) pool during development, we performed single-cell RNA-sequencing on mouse germ cells isolated from

NIAID Data Ecosystem50

Graded Nodal/Activin Signaling Governs ES Cell Fate Decisions via Differential Recruitment of Phospho-Smad2 to Oct4 and Distinct Target Gene Subsets

细胞命运决定

Activin信号通路

Nodal and Activin are morphogens of the TGFbeta superfamily of signaling molecules that direct differential cell fate decisions in a dose- and distance-dependent manner. During early embryonic develop

NIAID Data Ecosystem40

Histone posttranslational modifications and cell fate determination: Lens induction requires the lysine acetyltransferases CBP and p300

组蛋白修饰

细胞命运决定

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem30

Phosphorylated Groucho delays differentiation in the follicle stem cell lineage by providing a molecular memory of EGFR signaling in the niche

细胞信号传导

细胞命运决定

In the epithelial follicle stem cells (FSCs) of the Drosophila ovary, Epidermal Growth Factor Receptor (EGFR) signaling promotes self-renewal, whereas Notch signaling promotes differentiation of the p

DataONE2020-06-24 更新50

SRRM2 splicing factor modulates cell fate in early development [RNA-Seq]. SRRM2 splicing factor modulates cell fate in early development [RNA-Seq]

细胞剪接调控

细胞命运决定

Srrm2 splicing factor is a novel gene implicated in developmental disorders and diseases. However, the role of Srrm2 in early mammalian development remains unexplored. Here, we show that Srrm2 express

NIAID Data Ecosystem30

Lsd1 coordinates trophoblast development by retaining stem cells in their niche and directing cell fate

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