Our understanding of the origin and early evolution of life is generally studied under two different paradigms: bottom up and top down. Prebiotic chemistry and early Earth geochemistry allow researche
Input files to run the cytochrome bc1 simulations, related to the following publication: Purhonen, J., Grigorjev, V., Ekiert, R. et al. A spontaneous mitonuclear epistasis converging on Rieske Fe-S
shows non-zero minimal/maximal optimization coefficients computed by objective variability analysis (OVA) for each reaction from simulated glycerol-limited E. coli fluxes. (XLSX 9 kb)
