相关数据集
Allele-specific aberration of imprinted domain chromosome architecture associates with large offspring syndrome [4C-Seq]
Large offspring syndrome (LOS) and Beckwith-Wiedemann syndrome are a similar epigenetic congenital overgrowth conditions in ruminants and humans, respectively. We have reported global loss-of-imprint
NIAID Data Ecosystem70
Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promoters
Hypoxia inducible factor (HIF) directs an extensive transcriptional cascade that transduces numerous adaptive responses to hypoxia. Pan-genomic analyses, using chromatin immunoprecipitation and transc
NIAID Data Ecosystem50
Genetic Evidence for Asymmetric Blocking of Higher-Order Chromatin Structure by CTCF/Cohesin. Genetic Evidence for Asymmetric Blocking of Higher-Order Chromatin Structure by CTCF/Cohesin
The architectural protein CTCF binds to mammalian insulators genome wide with directionality and recruits cohesin to mediate oriented long-distance chromatin loops. In many cases, CTCF-binding sites (
NIAID Data Ecosystem40
Additional file 3: Table S2. of Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2
Summary of median magnitude of change, direction, and number of df DIRs for viewpoints 1, 2, 11, and 12. Notice how viewpoint 1 displays an increase in contact probabilities with surrounding sequences
NIAID Data Ecosystem70
High resolution Hi-C analysis in S. pombe reveals fundamental elements of genome architecture [microarray CGH]. Schizosaccharomyces pombe
Eukaryotic genomes are folded into three-dimensional structures that govern diverse hromosomal procsses. Studeis in Drosophila and mammals have revealed large self-associating tomological domains whos
NIAID Data Ecosystem40
