IL-22 deficiency had minimal effect on gene expression in the mouse during <i>H</i>. <i>pylori</i> infection.

At 1 months post infection, no significant difference in expression of Defb3 (p = 0.524), Lcn2 (p = 0.31), S100a8 (p = 0.944), S100a9 (p = 0.31), Cxcl1 (p = 0.413), Cxcl2 (p = 0.944) and Cxcl5 (p = 0.532) as measured between H. pylori–infected WT and infected IL-22-/- mice gastric tissue. Relative units are calculated as described in the methods, relative to GAPDH and calibrated to uninfected WT mice. Statistical analysis was performed using Mann-Whitney U (Error bars represent ± SEM).