Measurements are given in triplicate as OD600 for each isolate. The starting OD has been subtracted from the values to reflect active growth rates. (XLSX)
CFU values represent the mean (SD) of six replicates, and data were analyzed with one-way and two-way ANOVA at a significance level of 0.05. Values with the same superscript letter are not significant
We developed Statistical Coupling Analysis (SCA) for RNA which predicts allosteric networks, or sectors, in complex RNAs. We applied our analysis to the 23S rRNA as a test system and used it to make p