Automated Biomarker Discovery and Predictive Model

kaggle2025-10-24 更新2025-12-06 收录

免疫治疗生物标志物

药物响应预测建模

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**Abstract:** The efficacy of pembrolizumab, an immune checkpoint inhibitor, is

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2025-10-24

Tumor-intrinsic ST3GAL3 Activity Blunts Anti-tumor Immune and Drives Immunotherapy Resistance

肿瘤免疫逃逸

免疫治疗生物标志物

ST3GAL3 is a a2,3-sialyltransferase and involves in a2,3 sialylation in tumors; however, its role in the tumorigenic capacity of malignant cells and anti-tumor immune remains largely unexplored. Here,

NIAID Data Ecosystem50

Table3_Pan-cancer analysis identifies YTHDF2 as an immunotherapeutic and prognostic biomarker.XLSX

免疫治疗生物标志物

泛癌种分析

Background: N6-methyladenosine (m6A) modification is a dynamic and reversible post-transcriptional RNA modification prevalent in eukaryotic cells. YT521-B homology domain family 2 (YTHDF2) has been id

NIAID Data Ecosystem30

cf7cc097-bc4f-4000-aeff-f35090b902aa - samples

肿瘤基因组学

免疫治疗生物标志物

Whole exome sequencing BAM files of 50 metastatic solid tumour and matched blood germline DNA prior to pembrolizumab treatment.EGA dataset EGAD00001004873

NIAID Data Ecosystem20

DataSheet1_A Pan-Cancer Analysis of IRAK1 Expression and Their Association With Immunotherapy Response.docx

泛癌免疫分析

免疫治疗生物标志物

IRAK1 is an active kinase which plays a critical role in IL-1/TLR signaling pathway involved in inflammation and innate immune response. Recently, increasing evidence supports a potential role of IRAK

NIAID Data Ecosystem30

Comparison of the lymphocyte before and after the activation.

免疫治疗生物标志物

淋巴细胞基因表达分析

Immunotherapy using activated lymphocytes has recently been developed, but there is not yet the biomarker which can predict curative effect. In our recent study, we found that random migration is sign

NIAID Data Ecosystem30

Automated Biomarker Discovery and Predictive Model

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