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Transient Pairing of Homologous Oct4 Alleles Accompanies the Onset of Embryonic Stem Cell Differentiation

ChEBI2015-02-03 更新2026-07-21 收录

胚胎干细胞分化

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-65510 数据链接链接失效反馈

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Transient Pairing of Homologous Oct4 Alleles Accompanies the Onset of Embryonic Stem Cell Differentiation

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创建时间：

2015-02-03

表观遗传调控

木质素生物合成响应

Lignin is one of the most important secondary metabolites and essential to the formation of cell walls. Changes in lignin biosynthesis have been reported to be associated with environmental variations

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Maintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (K9 KO ChIP-Seq). Mus musculus

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胚胎干细胞发育

During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to

NIAID Data Ecosystem10

Study of 5mC-DNA, m6A-RNA and RNA-expression in HeLa, ES and EB [5mC in ES and EB]

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RNA-DNA甲基化互作

The epigenetic marking of DNA, histones, and RNA is central for regulating gene expression in development and disease. On DNA, well-characterized 5-methylcytosine (5mC) controls the chromatin state. O

NIAID Data Ecosystem00

Variant Polycomb complexes in Drosophila consistent with ancient functional diversity

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发育生物学

Polycomb group (PcG) mutants were first identified in Drosophila based on their failure to maintain proper Hox gene repression during development. The proteins encoded by the corresponding fly genes

NIAID Data Ecosystem20

A broad role of KMT2C/MLL3 in the transcriptional regulation of DNA repair components in cancer ChIPseq

DNA修复

表观遗传调控

Genome-wide studies in tumor cells have indicated that chromatin-modifying proteins are commonly mutated in human cancers. The lysine-specific methyltransferase 2C (KMT2C/MLL3) is a putative tumor sup

NIAID Data Ecosystem10

Transient Pairing of Homologous Oct4 Alleles Accompanies the Onset of Embryonic Stem Cell Differentiation

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