hTLR4 Cells were transfected a CRISPR/Cas9 construct and a gRNA specific for the rs17622517 locus. Wild type, heterozygous or homozygous clones were isolated and then treated with no LPS, LPS for 90 m
Genome-wide association studies have identified statistically significant associations between genetic variants in or near the IKZF1 gene and several autoimmune disorders. IKZF1, encoding the transcri
