The breast cancer promoting effects of estrogen and the chemopreventive effects of tamoxifen are thought to be mediated by the estrogen receptor, a ligand-dependent transcription factor. Therefore, co
Transcription factor binding motifs. We obtained 239 PWMs from three different data sources: (1) factor book motifs processed by ENCODE UCSC; (2) motifs downloaded from Factorbook; (3) HOCOMOCO Human
BackgroundThe tumor immune microenvironment (TIME) has been recognized to be an imperative factor facilitating the acquisition of many cancer-related hallmarks and is a critical target for targeted bi
Molecular targeted therapy has shown potential in hepatocellular carcinoma (HCC) patients, and immunotherapy applications are developing rapidly. However, clinical guidance for making individualized t
