Human Topoisomerase I (hTop1p) is a ubiquitous enzyme that relaxes supercoiled DNA through a conserved mechanism involving transient breakage, rotation, and binding. Htop1p is the molecular target of
Histone acetyltransferases (HATs) and histone deacetylases (HDACs) are enzymes that exhibit an important transcription activity. Dysfunction of these enzymes may lead to different diseases including c
Results of a docking-MD virtual screening study investigating the binding of licensed medicinal compounds with loop D of human AQP1. This folder contains docking results and analysis, MD input and out
