In this study the Itolizumab treated group is compared to control treated group across days in polarizing conditions Agilent Custom Human Gene Expression 8X15k (AMADID: 16332) designed by Genotypic Te
Increased lactate levels in the tissue microenvironment are a well-known feature of chronic inflammation. However, the role of lactate in regulating T cell function remains controversial. We here demo
We investigated how IL-1β and anti-CD3/CD28 stimulation affected gene expression in IL-1RI+ and IL-1RI- Th17 cells by RNA sequencing. Overall design: IL-1RI+ and IL-1RI- Th17 cells were sorted from th
We report transcriptional profiling of mouse Th17 cells activated and expanded in vitro in the presence of Th17-inhibitory bacterial metabolites 3-oxoLCA and isoLCA. Naïve CD4 T cells from C57BL/6J m
to study the effects of PSGs on the Th17 polarization of CD4+ cells Conclusion: Native human pregnancy-specific β1-glycoprotein preparation (PSG) at a concentration of 100 µg/mL was shown to decrease
