Replication Gaps are a key determinant of PARP inhibitor Synthetic Lethality with BRCA deficiency. Cong et al.
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Additional file 1: of Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer
â Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancerâ Additional results on predicted synthetic lethal genes. (XLSX 963 kb)
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DepMap Datasets for WRN manuscript
Cancer Dependency Map (DepMap) data used for analyses in the manuscript "WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers" by Chan and Shibue et al. is packaged into an rds
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Crystal structure of the catalytic domain of human PARP1 in complex with inhibitor EB-47
Crystal structure of the catalytic domain of human PARP1 in complex with inhibitor EB-47 Descriptor: 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1
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Genes identified as congruent to XopE2.
A plus sign marks an SL interaction between a congruent gene and a deletion strain hypersensitive to XopE2.aSL Overlap - the number of SL interactions with hypersensitive deletion strains.bTotal SL -
Figshare2015-12-02 更新50
Additional file 1: of Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancer
â Inferring synthetic lethal interactions from mutual exclusivity of genetic events in cancerâ Additional results on predicted synthetic lethal genes. (XLSX 963 kb)
DataCite Commons2024-12-13 更新50
