Characterization of five lead candidates selected for <i>in vivo</i> testing.
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In vitro activity on P. falciparum 3D7, NTS, adult S. mansoni, cytotoxicity on MRC5-cells, and pharmacokinetic parameters* of 5 active compounds selected for in vivo studies identified in 2 parallel screens at the Swiss TPH and LSHTM. PK parameters are unpublished data, In vitro activity on P. falciparum 3D7 and cytotoxicity on MRC5-cells can be found at http://www.mmv.org/research-development/malaria-box-results.
创建时间:
2014-01-09



