The Transcription factor Zeb2 ia required to maintain tissue-specific identities of macrophages

NIAID Data Ecosystem2026-03-14 收录

巨噬细胞分化

转录因子调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE117081 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2022-10-27

TFAP2A ChIP-seq in human primary melanocytes. Homo sapiens

黑色素细胞

转录因子调控

Mutations in the gene encoding transcription factor TFAP2A result in pigmentation anomalies in model organisms and premature hair graying in humans. However, the pleiotropic functions of TFAP2A and it

NIAID Data Ecosystem60

anti-Eomes ChIPseq of control OT-I cells and Eomes-overexpressing OT-I cells. anti-Eomes ChIPseq of control OT-I cells and Eomes-overexpressing OT-I cells

转录因子调控

T细胞耗竭

High amount of Eomes might drive T cell exhaustion. In order to understand how Eomes contributes to exhaustion of CD8+ T cell in the TME as a transcription factor, we conducted anti-Eomes ChIPseq anal

NIAID Data Ecosystem30

Expression data of RAW264.7 cells cultured in conditioned medium of SCR or JMJD6-KO PymT-41C cells

肿瘤微环境

巨噬细胞分化

In our study we showed that JMJD6 expression in tumor cells can regulate macrophage differentiation in vitro through ANXA-1 secretion. For this experiment we cultured RAW264.7 cells cultured in condit

NIAID Data Ecosystem20

Trasncripional regulation by overexpression of constitutively active FOXO1 (CA-FOXO1) in human endothelial cells. Trasncripional regulation by overexpression of constitutively active FOXO1 (CA-FOXO1) in human endothelial cells

转录因子调控

内皮细胞基因表达

To identify genes regulated by FOXO1, we performed RNA-seq analysis of human unbilical vein endothelial cells (HUVECs) overexpressing CA-FOXO1 by adenovirus. CA-FOXO1 is constructed by mutating three

NIAID Data Ecosystem40

MH003B:FOXO3 in control of circadian rhythms via direct regulation of Clock. Part 2: knockdown of FoxO3.. Mus musculus

生物钟机制

转录因子调控

Circadian rhythms are responsive to a variety of external cues, light and metabolism being the most important. In mammals, the light signal is sensed by the retina and transmitted to the SCN master cl

NIAID Data Ecosystem30

The Transcription factor Zeb2 ia required to maintain tissue-specific identities of macrophages

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