Crystal structure of inactive HIV-1 protease variant (I50V/A71V) in complex with p1-p6 substrate variant (R452S) Descriptor: PHOSPHATE ION, Protease, SULFATE ION, ... Authors: Lin, K.H, Schiffer, C.A.

Protein Data Bank Japan2024-02-28 更新20

Compounds tested against Dengue and may be useful for Zika virus

抗病毒药物

虫媒病毒药物发现

Some compounds from papers on Dengue - this file will be expanded in future..Suplemental data for Open Drug Discovery for the Zika virus

Figshare2016-02-03 更新00

Inhibition of SFV and SINV replication by selected hit compounds measured by CPE reduction and virus production assays.

抗病毒药物

病毒复制抑制

aIC50 values against SFV and SINV were determined in dose-response experiments using an assay for the reduction of cytopathic effect. A concentration range from 200 µM to 0.1 µM was applied for each c

Figshare2015-12-02 更新20

Exploring the molecular mechanism of action of a mono-herbal formulation of Ayurveda Cesamplous pareira. Exploring the molecular mechanism of action of a mono-herbal formulation of Ayurveda Cesamplous pareira

中药分子药理学

药物重定向

Drugs used in traditional medicine are multisystemicand hence are amenable to repurposing. This coupled with the history of safe usage make it possible for practitioners to rapidly evolve therapies fo

NIAID Data Ecosystem10

Approved antibiotics screened for candidate anti-Ebola drugs

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