Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform
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Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform Descriptor: 2-methyl-1-(4-{2-[1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl]-4,5-dihydro[1]benzoxepino[5,4-d][1,3]thiazol-8-yl}-1H-pyrazol-1-yl)propan-2-ol, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Authors: Murray, J.M, Rouge, L, Wu, P. Deposit date: 2013-02-11 Release date: 2013-08-28 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase beta isoform. Bioorg.Med.Chem.Lett., 23, 2013
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2013-02-11
