Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants

NIAID Data Ecosystem2026-03-11 收录

细胞代谢调控

线粒体功能遗传学

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE140354 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2019-11-20

Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion

HIV-1病毒融合机制

细胞代谢调控

There has been resurgence in determining the role of host metabolism in viral infection yet deciphering how the metabolic state of single cells affects viral entry and fusion remains unknown. Here, we

NIAID Data Ecosystem30

GSH-deficiency promotes basal hyperinsulinemia in the insulin secreting cell line INS-1

胰岛素分泌机制

细胞代谢调控

This study sought to determine the impact of glutathione (GSH) synthesis on beta-cell function. To induce GSH deficiency, GCLC was inhibited in INS-1 cells using buthionine sulfoximine (BSO). The 24-h

NIAID Data Ecosystem10

Essential and non-overlapping IL-2Ra-dependent signaling for thymic development and peripheral homeostasis of regulatory T cells

免疫调节性T细胞

细胞代谢调控

IL-2R signaling is essential for regulatory T cell (Treg) function. However, the precise contribution for IL-2 during Treg thymic development, peripheral homeostasis, and lineage stability remains unc

NIAID Data Ecosystem10

DataSheet1_Epigenetic Modifier Supplementation Improves Mitochondrial Respiration and Growth Rates and Alters DNA Methylation of Bovine Embryonic Fibroblast Cells Cultured in Divergent Energy Supply.docx

表观遗传修饰

细胞代谢调控

Epigenetic modifiers (EM; methionine, choline, folate, and vitamin B12) are important for early embryonic development due to their roles as methyl donors or cofactors in methylation reactions. Additio

NIAID Data Ecosystem20

Expression data from C2C12 myotubes treated with sugarcane top ethanolic extract (STEE) and control C2C12 myotubes.. Expression data from C2C12 myotubes treated with sugarcane top ethanolic extract (STEE) and control C2C12 myotubes.

细胞代谢调控

线粒体功能

The aim of the study was to obtain the data on the changes brought by STEE in in vitro myotubes, with a focus on metabolism and mitochondria, to explore its unknown functional properties. In this stud

NIAID Data Ecosystem10

Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants

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