BackgroundHypofunction of the glutamate N-Methyl-d-aspartate (NMDA) receptor has been implicated in the pathophysiology of schizophrenia. p250GAP is a brain-enriched NMDA receptor-interacting RhoGAP.
CHR = Chromosome; SNP = Single Nucleotide Polymorphism; EA = Effect Allele; RA = Reference Allele *SNP is on gene; EAF = Effect Allele Frequency for Controls; OR = Odds Ratio; CI = Confidence Interval
For each CHD region, we list results for each score (-log in base 10 of the p-value) for the originally implicated genotyped SNP, the imputed (* denotes imputed SNPs) or genotyped SNP producing the mo
ObjectiveInterferon (IFN) signaling plays a crucial role in autoimmunity. Genetic variation in interferon regulatory factor 5 (IRF5), a major regulator of the type I interferon induction, has been ass
