CPD

The Cellular Phenotype database stores data derived from high-throughput phenotypic studies and its aim is to provide easy access to phenotypic data and facilitate the integration of independent phenotypic studies. Through its interface, users can search for a gene of interest, or a collection of genes, and retrieve the loss-of-function phenotypes observed, in human cells, by suppressing the expression of the selected gene(s), through RNA interference (RNAi), across independent phenotypic studies. Similarly, users can search for a phenotype of interest and retrieve the RNAi reagents that have caused such phenotype and the associated target genes. Information about specific RNAi reagents can also be obtained when searching for a reagent ID.

细胞表型数据库（Cellular Phenotype database）存储源自高通量表型研究的数据，旨在实现表型数据的便捷获取，并推动独立表型研究的整合。通过其交互界面，用户可检索目标基因或基因集合，获取在各类独立表型研究中，通过RNA干扰（RNA interference, RNAi）抑制选定基因表达后，人类细胞内观测到的功能丧失型表型。同理，用户可检索目标表型，获取引发该表型的RNAi试剂及其对应的靶基因。通过搜索试剂编号，用户亦可获取特定RNAi试剂的相关信息。

搜集汇总

背景与挑战

背景概述

CPD（细胞表型数据库）存储来自高通量表型研究的数据，旨在提供易于访问的表型信息并促进独立研究的整合。用户可通过基因、表型或试剂ID进行搜索，检索基于RNA干扰技术的人类细胞功能缺失表型数据。