We have obtained fibroblast cultures from old adult human control donors and Alzheimer patients. The fibroblasts were reprogrammed into directly induced neurons (iNs) to serve as an adult-like and age
As a characteristic of hydrogen bonds, the stability of hydrogen bonds was calculated as the number of conformations in which the bond was present, referred to the total number of conformations. A tab
Shown are results from the siRNA screen for one of the four significant SMG1 siRNAs. p-syn is shown in red and t-syn in green. The level of p-syn and t-syn as a percent of expression seen in control n
MIHFGN segment 137-142 from mouse prion Descriptor: Major prion protein Authors: Apostol, M.I, Sawaya, M.R, Eisenberg, D. Deposit date: 2010-07-08 Release date: 2011-03-02 Last modified: 2024-02-21 Me
Microarray and metabolomic analysis has been applied to the study of ALS in order to investigate how a Y374X TDP43 truncation mutation leads to an altered metabolic profile in fibroblasts driven by py
