BackgroundThe aging population is rapidly increasing, leading to physical decline and higher risks of chronic diseases, including sarcopenia, which adversely affects muscle quality and strength. Yi Ji
In problems with large amounts of missing data one must model two distinct data generating processes: the outcome process, which generates the response, and the missing data mechanism, which determine
Analysis of variance by Kruskall-Wallis method with Dunn’s test for statistical significance.The influence of alpha ketoglutarate (AKG 10 mM or 25 mM). A comparison of statistical significance between
This article proposes a phase I/II clinical trial design for adaptively and dynamically optimizing each patient’s dose in each of two cycles of therapy based on the joint binary efficacy and toxicity
