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Association between nuclear phospho-EGFR and pathological classification.

Figshare2015-12-02 更新2026-04-29 收录

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Association between nuclear phospho-EGFR and pathological classification.

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2015-12-02

EGFR信号通路

间充质干细胞转录组学

Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goal of this study is to analyse the whole transcriptome of MSCs stimulated with TGFα in o

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A synonymous germline variant in a gene encoding a cell adhesion molecule is associated with cutaneous mast cell tumour development in Labrador and Golden Retrievers

犬类遗传病

罕见癌症分子病理学

Mast cell tumours are the most common type of skin cancer in dogs, representing a significant concern in canine health. The molecular pathogenesis is largely unknown, but breed-predisposition for mast

NIAID Data Ecosystem100

K120R mutation inactivates p53 by creating an aberrant splice site leading to nonsense-mediated mRNA decay

p53基因突变机制

罕见癌症分子病理学

The point mutation that substitutes lysine with arginine at position 120 of human p53 has been characterized as a missense mutation. The K120R mutation renders the p53 protein disabled for acetylation

NIAID Data Ecosystem70

Astrocytes in response to activation of EGFR

星形胶质细胞

EGFR信号通路

Primary cultures of astrocytes from rat optic nerve heads were treated with EGFR ligand, EGF. Two cell lines from two different rat donors were used. The sister cell cultures were set as control and E

NIAID Data Ecosystem130

EGFR controls Drosophila tracheal tube elongation by intracellular trafficking regulation

EGFR信号通路

气管发育

Development is governed by a few conserved signalling pathways. Amongst them, the EGFR pathway is used reiteratively for organ and tissue formation, and when dysregulated can lead to cancer and metast

NIAID Data Ecosystem80

Association between nuclear phospho-EGFR and pathological classification.

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