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Efficient Synthesis of Maleimides and Carbazoles via Zn(OTf)<sub>2</sub>-Catalyzed Tandem Annulations of Isonitriles and Allenic Esters

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NIAID Data Ecosystem2026-03-06 收录
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Lewis acid Zn(OTf)2-catalyzed tandem annulations of isonitriles and allenic esters which lead to efficient and flexible syntheses of a range of biologically significant maleimides and carbazoles and related compounds are reported. A mechanistic rationale is proposed to account for the observed reactivity.

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2016-06-03
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