A very short and efficient synthesis of protected derivatives of APTO and AETD, the complex polyhydroxylated β-amino acid residues present in microsclerodermins C, D, and E, is described. The targets
Stereodefined monocyclic, spirobicyclic, and bis-spirotricyclic pyrazolidin-3-ones can be prepared efficiently by a three-component reaction involving a 1,3-dipolar cycloaddition of azomethine imines
