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Crystal Structure of ITK kinase bound to an inhibitor

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Protein Data Bank Japan2024-03-20 更新2026-03-21 收录
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Crystal Structure of ITK kinase bound to an inhibitor Descriptor: 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide, N-(6-oxo-1,6-dihydro-3,4'-bipyridin-5-yl)benzamide, Tyrosine-protein kinase ITK/TSK Authors: Brown, K, Cheetham, G.M.T. Deposit date: 2011-01-25 Release date: 2011-06-22 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery and structure-activity relationship of 3-aminopyrid-2-ones as potent and selective interleukin-2 inducible T-cell kinase (Itk) inhibitors J.Med.Chem., 54, 2011

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2011-01-25
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