Effect of 2-Phenylnaphthalenes PNAP-1−PNAP-8, Their Demethylation Derivatives PNAP-2h−PNAP-7h, and Amino PNAP-8h on the Viability of MCF-7 Cells.

The MCF-7 cell line was treated with PNAP-1−PNAP-8, and PNAP-2h−PNAP-8h at eight concentrations and then incubated at 37°C for 48 h. The cell viability was examined via the MTT assay.a The number of viable cells remaining after PNAP treatment is expressed as a percentage of the vehicle control, which was arbitrarily assigned a value of 100.0%. The results are presented as the means ± SEM from three independent assays.*PEffect of 2-Phenylnaphthalenes PNAP-1−PNAP-8, Their Demethylation Derivatives PNAP-2h−PNAP-7h, and Amino PNAP-8h on the Viability of MCF-7 Cells.