16S rRNA of fecal, rectal swab and tissue biopsy microbiota in patients with inflammatory bowel disease

This study aimed to evaluate differences in the microbiota at these sites in patients with inflammatory bowel disease. 33 Crohns disease, 54 ulcerative colitis, and 21 non IBD patients were enrolled when surveillance colonoscopy was scheduled. Samples of colon biopsy tissues, rectal swabs during colonoscopy, and feces before bowel preparation were collected to analyze microbial composition.