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Live-Cell Imaging of Pol II and Elongation Factors Distinguish Competing Mechanisms of Transcription Regulation. 14. Versluis et al.

Name: Live-Cell Imaging of Pol II and Elongation Factors Distinguish Competing Mechanisms of Transcription Regulation. 14. Versluis et al.
Creator: Cornell University; University of California Berkeley; Hofstra University
Published: 2026-04-09T12:25:56+08:00

Mendeley Data2026-04-09 收录

活细胞成像

转录调控机制

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Supplemental Figure 7C Raw Data

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提供机构：

Cornell University; University of California Berkeley; Hofstra University

转录调控机制

胚胎干细胞表观遗传学

Ssu72 is a Ser5P-RNAPII phosphatase, nevertheless few targets have been characterized and its role in mammal cells remains elusive. Using ChIPseq and GROseq technologies we aimed to identify Ssu72 tar

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转录调控机制

Cyclin-dependent kinases (CDKs) that have critical roles in RNA polymerase II (Pol II)-mediated gene transcription are emerging as therapeutic targets in cancer. We have previously shown that THZ1, a

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Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors [Affymetrix]. Homo sapiens

激酶抑制剂开发

转录调控机制

Cyclin-dependent kinases 12 and 13 (CDK12 and CDK13) play critical roles in the regulation of gene transcription. However, the absence of CDK12 and CDK13 inhibitors has hindered the ability to investi

NIAID Data Ecosystem20

Homo sapiens epigenomics. Homo sapiens strain:Hela cells

转录调控机制

RNA聚合酶转录

genomic DNA and mRNA from Hela cells To analyzed transcriptional regulation in Hela cells, we performed RNASeq and ChIPSeq using monoclonal antibodies which react Ser2P or Ser5P of RNAP2 specifically.

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Promoter-specific changes in initiation, elongation and homeostasis of histone H3 acetylation during CBP/p300 Inhibition [GRO-Seq]. Promoter-specific changes in initiation, elongation and homeostasis of histone H3 acetylation during CBP/p300 Inhibition [GRO-Seq]

转录调控机制

表观遗传学

Regulation of RNA Polymerase II (Pol2) elongation in the promoter proximal region is an important and ubiquitous control point for gene expression in metazoans. We report that transcription of the ade

NIAID Data Ecosystem20

Live-Cell Imaging of Pol II and Elongation Factors Distinguish Competing Mechanisms of Transcription Regulation. 14. Versluis et al.

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